| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate |
2000-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f677dfda8496c6b56fb1c306d1e5f2b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1769421243fe725073a94bd9a5fe9292 |
| publicationDate |
2001-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001169783-A |
| titleOfInvention |
Method for measuring action on leptin receptor |
| abstract |
(57) [Summary] [PROBLEMS] To provide a method and the like for measuring the action of a test substance on a leptin receptor. A method for measuring the action of a test substance on a leptin receptor, comprising the following steps. (1) culturing mammalian cells containing the following regions (a) to (c) and having a chimeric receptor capable of binding to leptin and exhibiting leptin-dependent growth: (a) a homodimer excluding the leptin receptor Intracellular region of receptor subunit selected from the group consisting of cytokine receptor subunit, interleukin-2 receptor β subunit and gp130 (b) Transmembrane region of cytokine receptor subunit (c) Extracellular region of leptin receptor subunit Region (2) a step of bringing the mammalian cell into contact with a test substance, and (3) a step of measuring the degree of growth of the mammalian cell |
| priorityDate |
1999-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |