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filingDate 1999-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14381043b87a6b6c0aaacbdf869c3b87
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publicationDate 2001-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2001139524-A
titleOfInvention Organic amine salt of (2S) -2-benzylsuccinic acid monoester and production method thereof
abstract PROBLEM TO BE SOLVED: To provide an organic amine salt of (2S) -2-benzylsuccinic acid monoester of high optical purity which is useful as a raw material for producing a pharmaceutical and a method for producing the same. SOLUTION: The general formula: (R 1 is lower alkyl) is catalytically reduced in the presence of a BPPM-Rh complex to give a compound of the general formula Is reacted with an organic amine of the general formula R 2 —NH 2 (R 2 is tert-butyl, cyclohexyl, 2-phenylethyl, benzyl) to obtain a compound of the general formula: Is obtained.
priorityDate 1999-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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