| abstract |
(57) [Problem] To provide a pharmaceutical composition for treating anxiety or depression. A pharmaceutical composition for treating anxiety or depression in a mammal, wherein (a) the anxiolytic agent or a compound exhibiting activity as an antidepressant, or a pharmaceutically acceptable agent, respectively. A salt thereof; (b) a CNS penetrant NK-1 receptor antagonist or a pharmaceutically acceptable salt thereof; and (c) a pharmaceutically acceptable carrier, wherein the active agent is a "and" b "are present in an amount that renders the composition effective in treating anxiety or depression, respectively. |