| titleOfInvention |
New 9- (3,5-dimethoxyphenyl) -5,8,8a, 9-tetrahydrofuro [3 ', 4': 6,7] naphtho [2,3-d] [1,3] dioxole-6 ( 5aH) -one compounds, processes for their preparation and pharmaceutical compositions containing them |
| abstract |
PROBLEM TO BE SOLVED: To provide a novel antitumor agent and cytotoxic agent, 9- (3,5-dimethoxyphenyl) -5, which have high activity in anticancer treatment, high solubility and high tolerance. , 8,8a, 9-tetrahydrofuro [3 ', 4': 6, 7] Naphtho [2,3-d] [1,3] dioxole-6 (5aH) -one compounds are provided. SOLUTION: In the formula, R represents a group of the formula (i) or the formula (ii); X and Y are hydrogen and the like; W is hydrogen and the like; G represents hydrogen or the like; R 1 Represents hydrogen or the like], a method for producing the compound, and a pharmaceutical composition containing the compound. Embedded image |