abstract |
(57) [Summary] The present invention relates to a compound represented by the general formula (I): [Wherein, Ar is a nitrogen-containing heteroaromatic group, X and Z are carbon atoms and the like, Y is CO and the like, R 1 is a hydrogen atom and the like, R 2 and R 3 are hydrogen atoms and the like, R 4 And R 5 represent a hydrogen atom or the like, and have the formula: Represents a single bond or a double bond], and a method for producing the compound. According to the present invention, since the compound of the present invention has a remarkable inhibitory effect on the growth of tumor cells, it provides a Cdk4 and / or Cdk6 inhibitor for treating malignant tumors. Can be. |