| abstract |
(57) Abstract: An α-substituted carboxylic acid derivative useful as a therapeutic and / or prophylactic agent for diabetes, impaired glucose tolerance, gestational diabetes, etc., a pharmaceutically acceptable ester thereof, or a pharmaceutically acceptable ester thereof. Or a pharmaceutically acceptable salt thereof. SOLUTION: General formula (I) (Wherein, R 1 represents an alkyl group or the like, R 2 represents a hydrogen atom or the like, R 3 represents a hydrogen atom or the like, A represents a ＣＨCH— group or the like, B represents an oxygen atom or the like, W 1 represents a C 1 -C 8 alkylene group, W 2 represents a single bond or a C 1 -C 8 alkylene group, X represents a hydrogen atom or the like, Y represents an oxygen atom or the like, Z 1 represents an alkoxy group or the like. Or a pharmacologically acceptable salt thereof, a pharmacologically acceptable ester thereof, or a pharmacologically acceptable amide derivative thereof. |