abstract |
(57) Abstract: The present invention relates to a mammalian recombinase modified so that its expression efficiency in a mammalian cell, tissue, organ, or body is several times higher than that of a phage-derived Cre recombinase gene. It is intended to provide a gene. To solve this problem, the present invention provides a mammalian type Cr comprising codons frequently used in mammalian cells. Provide the e recombinase gene. |