| abstract |
(57) Abstract: strong serotonergic 5HT 2B / 5HT 2C activity and in particular with a 5HT 2C antagonist activity, Depression, psychosis, schizophrenia, phobia, anxiety, panic attacks, sleep disorders, appetite disorders, impulsive and aggressive disorders, Provided are medicaments useful for treating sexual disorders, as well as migraine. SOLUTION: Formula (I): [Wherein ---- is a single bond or the like; R 1 is hydrogen or the like; R 2 Is cyano and the like; R 3 and R 4 are taken together (C 3 -C 10) cycloalkyl is formed; R 5 is a hydrogen atom or the like; Ra to Rd, a compound of the representative of such hydrogen], a method of manufacturing the same, and pharmaceutical compositions containing them. |