| abstract |
(57) [Problem] To provide a novel production method suitable for industrial production of a cyanoalcohol derivative useful as a pharmaceutical intermediate. SOLUTION: A cyano alcohol derivative (I) is produced by introducing a cyanocarboxylic acid derivative (II) into a mixed acid anhydride (III), and then reducing the same with sodium bis (2-methoxyethoxy) aluminum hydride. Embedded image (In the formula, R 1 , R 2 and R 3 each represent a substituent, and n and m each represent 0 or an integer of 1 to 6.) |