abstract |
(57) [Summary]nPROBLEM TO BE SOLVED: To provide a preventive or therapeutic drug for diabetic complications. Offer.nSOLUTION: The formula [I]nEmbedded imagen [Where A isnEmbedded imagen {M, n, n 1 And n Two Is independently 0-3, R 1 Is C (O) OR 6 Etc., R Two Is a hydrogen atom, NR Ten R 1 0 ' , N + R 11 R 11 ' R 11 '' Etc., R Three And R 3 ' Is independently C 1-7 Alkyl group, R Four Indicates a protecting group, etc. You. Represents D, and D is a covalent bond, -NR 12 -Etc., X 1 ~ X Five Is independently a nitrogen atom, CR Five {R Five Is hydrogen atom, halogen Atom, -EG (E is -L 1 -(CR 13 R 13' ) k -L Two -(CR 14 R 14' ) l -L Three -(K represents 1 to 10, l represents 0 to 10, R 13 , R 13' , R 14 , And R 14' Independently represents a hydrogen atom or a halogen atom, etc. Represents, L 1 ~ L Three Independently represents a covalent bond, -O-, or the like. ) And G is C 6-14 Represents an aromatic group. ). } Represent. ] Or a salt thereof. |