| abstract |
(57) [Summary] (Modified) [Problem] To be able to deliver at least one kind of anionic substance of interest, particularly nucleic acid, into cells and to find application to gene therapy in vivo. To provide novel conjugates. (I) at least one first polypeptide capable of binding to an anionic substance; i) A complex for delivering a target anionic substance into a cell, comprising a target anionic substance, wherein the first polypeptide is derived from a C1 complement factor subunit amino acid sequence. The complex and a method for producing the complex, comprising all or a part of an amino acid sequence selected from the group consisting of: A pharmaceutical composition for delivering a target anionic substance to cells, comprising at least one of the above-mentioned complexes, and further comprising at least one adjuvant. Use of the conjugate for producing a pharmaceutical composition for the treatment, prevention or vaccine treatment of humans or animals. |