abstract |
(57) [Problem] To provide a method for producing optically active 1-aryl-1,2,3,4-tetrahydroisoquinolines. SOLUTION: General formula (1) Reacting a 1-aryl-3,4-dihydroisoquinoline represented by the formula with hydrogen in the presence of a complex of a Group VIII transition metal and an optically active phosphine compound. A method for producing an optically active 1-aryl-1,2,3,4-tetrahydroisoquinoline represented by the formula: |