| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9a22cb722665f16cb4424a7f04e7465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef3e73bf82e05dd388bd59b6da624736 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
1999-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780b5e0d2efb58ea9881e97061134be9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e823a44723f16265d2c19885e15bfd71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ce82661367a401aa0368b2897839b06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_276b74d238017e83b72726b36f57c053 |
| publicationDate |
2001-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001025390-A |
| titleOfInvention |
Apoptosis-inducing protein gene |
| abstract |
(57) [Problem] To provide a nucleic acid encoding a protein having an apoptosis-inducing action derived from a butterfly of the genus Pieris. Another object of the present invention is to provide a gene therapy agent for malignant tumor. SOLUTION: Using a PCR primer corresponding to a partial amino acid sequence of Pierisin purified and isolated from a butterfly of the genus Pieris, a cDNA encoding the full length of Pierisin is cloned, and the cDNA is expressed in a cell-free system. The apoptotic cell death activity on cancer cells was examined, and it was confirmed that the expressed protein had the same molecular weight as that of Pierisin derived from Pieris sp. But had the same apoptosis-inducing activity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018131718-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018007569-A |
| priorityDate |
1999-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |