http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001002690-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9fa13c33b79ba86e25d61d5e3cee4f2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558 |
| filingDate | 1999-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_972bcd37f148b5e0be2eff002d6d8971 |
| publicationDate | 2001-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001002690-A |
| titleOfInvention | Method for producing phosphoric diester |
| abstract | (57) [Problem] To provide an excellent method for producing tocopherol and ascorbic acid-2-phosphate diester. A compound obtained by reacting an α, β, γ or δ-tocopherol with a halophosphate esterifying agent, When reacting ascorbic acid or ascorbic acid having a protecting group at the hydroxyl group at the 5,6-position, as a deoxidizing agent, Using an alkali metal hydroxide or carbonate or a tertiary amine in an equivalence ratio of at least 3 in an organic solvent having a high affinity for water, then ascorbin having a protecting group at the hydroxyl group at the 5- or 6-position In the case of an acid, a method for producing a phosphoric diester represented by the following formula (I) or a pharmacologically acceptable salt thereof, wherein the protecting group is eliminated. Embedded image [Wherein, R 1 and R 2 are the same or different and each represent a hydrogen atom or a methyl group. ] |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8143437-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6927036-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021043489-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7560483-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114616264-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03077902-A1 |
| priorityDate | 1999-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.