| abstract |
(57) [Problem] To provide an anti-fibrotic agent containing PC-SOD. SOLUTION: An antifibrotic agent comprising lecithinated superoxide dismutase represented by the following general formula (I), which is administered in combination with a steroid drug. SOD ′ (QB) m (I) (where SOD ′ represents a residue of superoxide dismutase, Q represents a chemical crosslink, and B represents the hydroxyl group of lysolecithin having a hydroxyl group at the 2-position of glycerol. Represents a residue excluding a hydrogen atom, and m represents an average number of lysolecithin bonds to one molecule of superoxide dismutase, and represents a positive number of 1 or more.) |