| abstract |
(57) [Summary] [Problem] To measure protease activity contained in a sample, At the same time, a method is provided for obtaining information on the abundance and distribution of protease proteins and other substances. SOLUTION: This is a method for simultaneously performing protease activity measurement and immunohistochemical observation, wherein (1) a step of contacting a sample containing a protease with a thin film containing a protease substrate and formed on the surface of a support; (2) detecting a digestion mark formed on the thin film by the action of a protease by staining the thin film with a dye; and (3) A method comprising the step of using an antibody that reacts with a specific substance in a sample to visualize the substance. |