| abstract |
The present invention provides several novel compounds, compositions, and methods of treating a mammal by blocking the mammalian adenosine receptor, comprising administering at least one compound of the present invention. I do. Examples of compounds of the present invention include certain flavonoids of formulas (I) and (II) wherein R 1 to R 4 are as defined in the specification and M is —CH (OH) —CH (R 2 Or -C (OH) = C (R 2 )-, wherein R 1 and R 2 are as defined in the specification; or a dihydropyridine of formula (III) wherein R 2 to R 6 Is as defined in the specification); or a pyridine of formula (IV), wherein R 2 to R 6 are as defined in the specification; or a triazoloquinazoline of formula (V) , R 1 and R 2 are as defined herein); and their derivatives, or their pharmaceutically acceptable salts. |