| abstract |
(57) [Summary]nA vaccine composition comprising Bordetella pertussis (Pertactin) 69K outer membrane protein having 10-100 μg of 69K per 0.5 ml is described for the treatment of pertussis infection. In addition, combination vaccines containing 10-100 μg of 69K per 0.5 ml, in particular, the 69K component is formulated with linear hemagglutinin (FHA) and pertussis toxoid (PT), optionally with one or more other antigens, Also described are combined vaccines that may be combined with, for example, hepatitis B surface antigen, Haemophilus influenzae b (Hib), injectable polio (IPV) and hepatitis A. A method for preparing the vaccine is also described. |