| abstract |
(57) [Summary] The present invention relates to a compound represented by the general formula: Z 1 -KAQX 1 -KKNKNKHRHHSX 2 -TZ 2 (sequence No. 1) [wherein X 1 represents S or Y, X 2 represents T or I, Z 1 represents the N-terminal or 1 to 47 amino acids of the peptide, Z 2 is the C-terminal of the peptide, Represents a terminal amide group, or 1 to 77 amino acids], or one or more internal deletions, insertions or substitutions, and substantially retains the anticoagulant properties of Apo B-100 A variant of the peptide is provided. |