Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-838 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20 |
filingDate |
1997-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2000509277-A |
titleOfInvention |
Human hematopoietic stem cell and progenitor cell antigens and methods of use |
abstract |
(57) Abstract Hematopoietic progenitor cells and reagents, particularly antibodies that specifically bind to the antigen, are provided. Antigen expression is of high tissue specificity. It is simply detected based on a subset of hematopoietic progenitor cells from human bone marrow, fetal bone marrow and liver, cord blood and adult peripheral blood. The subset of cells recognized by AC133 is CD34 bright and contains substantially all of the CFU-GM activity present in the CD34 + population. This high specificity distribution of AC133 makes it very useful as a reagent for isolating and characterizing human hematopoietic progenitors and stem cells. Cells selected for expression of the AC133 antigen can be further purified by selection for other hematopoietic stem cell and progenitor cell markers. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008506637-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101608083-B1 |
priorityDate |
1996-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |