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filingDate 1997-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2000509252-A
titleOfInvention Monoclonal antibodies to detect cell killing antigen
abstract (57) Abstract: A monoclonal antibody that specifically binds to an antigen on a mitochondrial membrane in cell-depleted cells. The antigen is a 38 KD protein that can be detected in cells undergoing apoptosis but not in normal cells. The selectivity of this monoclonal antibody provides a way to distinguish between normal and apoptotic cells in a sample of a human hematopoietic cell population. Methods for detecting and measuring cells undergoing cell killing are also provided.
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