abstract |
(57) [Summary] The subject of the present invention is the following general formula (I): Where R 1 represents halogen, hydroxyl, (C 1 -C 8 ) alkyloxy or (C 1 -C 12 ) acyloxy, R 2 represents halogen or hydrogen, or R 1 and R 2 are Z is a double bond, and Z is an optionally substituted (C 1 -C 8 ) alkylthio, an optionally substituted arylthio group, a (C 1 -C 8 ) alkyloxy, halogen, cyano , Mercapto, thiocyanato, (CO 2 ) 0-1 —CO 2 H (which may be esterified), Y represents a hydrogen atom or a methyl group, and the dotted line at the 1-2 or 5-6 position is Compounds of the formula (1), which indicates that there may be two bonds, and their addition salts with acids or bases, their production methods, intermediates of this method and pharmaceutical compositions containing them. |