abstract |
(57) [Summary] The present invention relates to a low molecular weight mimetic of superoxide dismutase represented by the following formula. Wherein, R, R ', R 1 , R' 1, R 2, R '2, R 3, R' 3, R 4, R '4, R 5, R' 5, R 6, R '6, R 7 , R ' 7 , R 8 , R' 8 , R 9 , and R ' 9 and X, Y, Z and n are as defined herein. The compounds of the present invention are useful as therapeutics for inflammatory disease symptoms and disorders, ischemia / reperfusion injury, cerebral hemorrhage, atherosclerosis, inflammatory bowel disease and oxidant-induced tissue damage. |