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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04
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filingDate 1997-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2000-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2000504316-A
titleOfInvention Cellular and serum protein anchors for diagnostic imaging
abstract (57) [Summary]nThe present invention provides a non-invasive diagnostic method using a bivalent anchor molecule. The bivalent anchor molecule has a functional group that can be activated, and upon activation, this functional group forms a covalent bond with a reactive functional group on the target protein present in the mammalian vasculature. Binds to its target protein. The bivalent anchor also binds, directly or indirectly, to a diagnostic agent that provides the ability to diagnostically and non-invasively image the vascular space of a mammal. Vascular targets include both cell-associated and non-cell associated proteins present in the mammalian vasculature. This method has the ability to diagnostically image the vascular space of a mammal over an extended period of time, or, preferably, the ability to diagnostically image a particular cell type or compartment of the vascular space of a mammal for a number of applications. is there.
priorityDate 1996-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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