abstract |
SUMMARY The present invention relates to metastasis-inducing DNA, methods for identifying such DNA, and their use in diagnosis and therapy. The present invention provides a method for screening and recovering Met-DNA, comprising: (1) a benign, non-metastatic tumor when a fragment of human DNA derived from malignant, metastatic cancer cells is injected into a syngeneic animal; (2) injecting the transformed cells into syngeneic animals; (3) selecting animals with confirmed metastatic tumors; and (4) recovering Met-DNA therefrom. A method comprising the steps of: |