http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000502910-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8778 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 |
| filingDate | 1997-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2000502910-A |
| titleOfInvention | Bovine embryonic stem-like cells for producing transgenic ungulates, and methods of making and using the cells |
| abstract | (57) [Summary]nPrimordial germ cells are extracted from ungulate post-blastocyst embryos, just as primordial germ cells are extracted from gonad bumps of 25-day old pig embryos or 34-40 day old bovine embryos. Primordial germ cells are cultured in long-term culture (30 days or more) and give rise to cells similar to embryonic stem cells in morphology and in maintaining pluripotency. The cells can be maintained in culture for several months and manipulated genetically using homologous recombination techniques to insert the desired genetic material into the cell's genetic complement at the desired location. Genetically engineered cells can be inserted into blastocysts obtained from the same animal species from which the cells are derived to produce a chimeric ungulate. The chimeric ungulate can produce the desired pharmaceutical product via this genetic manipulation. |
| priorityDate | 1996-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 696.