http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000502671-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 |
filingDate | 1996-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2000502671-A |
titleOfInvention | Novel taxoids, their preparation and pharmaceutical compositions containing them |
abstract | (57) Abstract Novel taxoids of general formula (I), their preparation and pharmaceutical compositions containing them have been disclosed. In the general formula (I), Z is a hydrogen atom or a group of the general formula (II), wherein R 1 is an optionally substituted benzoyl, furoyl or thenoyl group or a group R 2 —O—CO 2 Wherein R 2 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted phenyl or heterocyclic; R 3 is alkyl, alkenyl, alkynyl , Cycloalkyl, cycloalkenyl, phenyl, naphthyl or an aromatic heterocyclic group; or R 4 is a hydrogen atom and R 6 and R 7 together form a ketone function; 5 together form a bond; or R 4 is hydrogen or hydroxy or alkoxy, alkenyloxy, optionally substituted Alkynyloxy, alkanoyloxy, aroyloxy, alkenoyloxy, alkinoyloxy, cycloalkanoyloxy, alkoxyacetyl, alkylthioacetyl, alkyloxycarbonyloxy, cycloalkyloxy, cycloalkenyloxy, carbamoyloxy, alkylcarbamoyl R 5 is a hydrogen atom or R 4 and R 5 together form a ketone function, R 6 is a hydrogen atom, and R and R 7 are together an oxy or dialkylcarbamoyloxy group; To form a bond. The novel products of the general formula (I) in which Z is a group of the general formula (II) have remarkable antitumor and antileukemic properties. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008523019-A |
priorityDate | 1995-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.