http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000501928-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 1996-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2000501928-A |
| titleOfInvention | Production of protein C in transgenic animals |
| abstract | SUMMARY A method for producing Protein C in a transgenic non-human mammal is disclosed. Protein C is converted from Lys-Arg to R 1 -R 2 -R 3 -R 4 (where R 1 -R 4 are individually Arg or Lys) between the L and H chains of protein C. Modified at the double-strand break. A DNA segment encoding the modified protein C is introduced into the germ cells of a non-human mammal, and the mammal or its female progeny produces milk containing protein C expressed from the introduced DNA segment. Protein C expressed from the introduced DNA segment, when activated, has anticoagulant activity. Non-human mammalian embryos and transgenic non-human mammals carrying DNA segments encoding heterologous protein C are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023171719-A1 |
| priorityDate | 1995-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 174.