http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000501118-A
Outgoing Links
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-529 |
filingDate | 1997-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2000501118-A |
titleOfInvention | Synergistic immunosuppressant composition containing 2,2'-bi-1H-pyrrole compound |
abstract | (57) [Summary] In immunosuppressant treatment, (a) immunosuppressant (A), and (b) formula (I) as a combined composition for simultaneous, separate or sequential use. [Wherein R 1 is hydrogen, phenyl, C 1 -C 20 alkyl, or C 2 -C 20 alkenyl (provided that the alkyl group and the alkenyl group are unsubstituted or identical, Or 1 to 3 different substituents, which are substituted with 1 to 3 substituents independently selected from halogen, C 1 -C 6 alkoxy, hydroxy, aryl, and aryloxy); 2 is hydrogen, C 1 -C 6 alkyl, cyano, carboxy, or is (C 1 -C 6 alkoxy) carbonyl; R 3 is halogen, hydroxy, or C 1 -C substituted with unsubstituted or phenyl 11 is alkoxy; R 4 is hydrogen, C 1 -C 6 alkyl, or phenyl; each of R 5 and R 6 are identical either, or different, are independently hydrogen, C 2 -C 20 alkanoyl , C 3 -C 20 alkenoyl, phenyl, C 1 -C 20 alkyl, or C 2 -C 20 alkenyl; alternatively, two of R 4 , R 5 , and R 6 together form a C 4 -C 12 polymethylene chain. (Wherein the polymethylene chain is unsubstituted or substituted with a C 1 -C 12 alkyl group, a C 2 -C 12 alkenyl group, or a C 1 -C 12 alkylidene group)]. A compound containing at least one immunosuppressant 2,2'-bi-1H-pyrrole compound (B) or a pharmaceutically acceptable salt thereof, wherein the immunosuppressant (A) or 2,2'-bi-1H -A composition having strong immunosuppressive activity against a substance containing either of the pyrrole immunosuppressive compound (B). |
priorityDate | 1996-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.