| abstract |
PROBLEM TO BE SOLVED: To reduce visceral fat and suppress visceral fat accumulation in humans or animals, prevent or ameliorate dyslipidemia, prevent or ameliorate dysglycemia, prevent or treat cancer, and a novel peroxy. Provided is a soma activator-responsive receptor agonist. A peroxisome activator-responsive receptor agonist has a conjugated triene structure (—CH ＝ C) in the molecule. H-CH = CH-CH = CH-) or a conjugated tetraene structure (-CH = CH-CH = CH-CH = CH-CH = C A conjugated unsaturated fatty acid having 10 to 26 carbon atoms having H-), Comprising at least one selected from salts and ester derivatives thereof, to promote binding of human and animal peroxisome activator-responsive receptors to target gene sequences, to promote downstream gene expression, It can reduce visceral fat and suppress visceral fat accumulation, prevent or improve lipid metabolism disorder, prevent or improve glucose metabolism disorder, and prevent or treat cancer. |