abstract |
(57) [Summary] [Problem] H. pylori useful for the development of a new diagnostic method for H. pylori. pylori "cytotoxin-associated immunodominant" antigen protein. A recombinant polypeptide that is immunogenic and has no functional contribution to toxicity, or a substantially low functional contribution to toxicity, having the following properties: A recombinant polypeptide comprising a contiguous sequence of at least 8 amino acids having: (1) the contiguous sequence of at least 8 amino acids comprises at least one site, wherein the site is a Helicobacter p and (2) the contiguous sequence of at least 8 amino acids is derived from the disclosed amino acid sequence. |