| abstract |
(57) Abstract: Obtain a compound capable of stabilizing the intrinsic β-sheet structure of a naturally occurring or synthetic peptide, protein or molecule. Kind Code: A1 Disclosed are β-sheet mimetics and methods for β-sheet mimetics for providing or stabilizing β-sheets of peptides, proteins or molecules. In one aspect, the β-sheet mimetic is covalently attached to or at the end of a peptide or protein length. β Sheet mimetics generally have utility as protease inhibitors with activity as serine protease inhibitors (eg, thrombin, elastase and factor X). |