| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C4-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-532 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C4-00 |
| filingDate |
2000-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5b6ed40d16f268a87e17bd607601850 |
| publicationDate |
2000-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2000319289-A |
| titleOfInvention |
Phosphine oxide vitamin D precursor |
| abstract |
PROBLEM TO BE SOLVED: To provide a method for producing a phosphine oxide of the formula 1, which can be used for efficient synthesis of a vitamin D analog. SOLUTION: (a) chlorinating a compound of formula 2 with triphosgene in the presence of an organic base to obtain a compound of formula 3, and (b) reacting the compound of formula 3 with a salt of diphenylphosphine oxide Thereby obtaining a compound of the formula 1. Embedded image Wherein Ph is phenyl; X 1 and X 2 are hydrogen and the like; R 1 is a protecting group; R 2 is fluorine and the like; Represents a bond that forms an adjacent double bond that is any of |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009508813-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010528099-A |
| priorityDate |
1999-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |