| abstract |
(57) Abstract: Formula (I) wherein A and B together form -C (O When H) = C (X 1 ) -C (Y 1 ) = C (OH)-(X 1 and Y 1 represent a hydrogen atom, a lower alkylthio group, a lower alkenylthio group, etc.), R 1 and R 2 represents an alkyl group, an aryl group, a heterocyclic group or the like, and A and B together form —C (R 3 ) (R 4 ) -C (X 2 ) = C (Y 2 ) -C (R 5 ) (R 6 )-(X 2 and Y 2 represent a hydrogen atom, an amino group, a lower alkylamino group, a lower alkenylamino group, etc .; 3 and R 4 represent a lower alkoxy group or together represent an oxygen atom; R 5 and R 6 represent a lower alkoxy group or together represent an oxygen atom) When represented, R 1 and R 2 represent a hydrogen atom, an alkyl group, a heterocyclic group, an aryl group, etc.] A quinoxaline derivative represented by or a salt thereof. Embedded image [Effect] It has a growth inhibitory activity on tumor cells, and is useful as an active ingredient of pharmaceuticals such as antitumor agents. |