| abstract |
(57) Abstract: (a) a hydrophilic drug having a basic group, an acidic group, or both, (b) an acidic group which forms an ion complex with the hydrophilic drug to enhance lipophilicity, A pharmaceutical composition for oral administration containing a compound having a basic group or both thereof or a salt thereof, and (c) a solvent for dispersing or dissolving the ion complex. [Effects] The gastrointestinal absorption of a drug having high hydrophilicity and low gastrointestinal absorption can be remarkably enhanced. |