abstract |
(57) [Summary]nThe present invention relates to an excellent anti-AIDS virus (HIV- 1) Novel modified oligodeoxyribonucleic acid having action An anti-AIDS agent containing otide is provided.nSOLUTION: General formulanEmbedded imagen [Wherein Q is R 1 R Two R Three Z group (wherein R 1 , R Two as well as R Three Is H, C1-4 alkyl, substitutable aryl, or Exchangeable anthraquinonyl; Z represents C or Si; Two , R Three And Z together form fluorenyl, xanthe Nyl); R Four Is H, C1-4 alkyl which can be substituted, Reel, replaceable aralkyl; Y 1 , Y Three , Y Four Is O, S, NH; Y Two Is O, S, NH, C1-4 alkylene, Phenylene; Z is C, Si; X is C1- 10 alkylenes; m and n are integers from 0 to 10; GGGGT, TGGGGT, TGGGGGGT, TGG GCG, TGGGGTG, TGGGG, TGGGGGG or Oligodeoxyribonucleotides with TGGGAG Or a pharmacologically acceptable compound represented by salt. |