| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate |
2000-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d94248c24501fd26624477f77ddb9a4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a64bf6acdb588478ad64f9df8b576c33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24b7bbf2c78a9ed4b18421df31bd6cf0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94592bc39be7cbd3bff1244d16135858 |
| publicationDate |
2000-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2000229887-A |
| titleOfInvention |
Pharmaceutical solid dispersion |
| abstract |
(57) [Problem] To provide a pharmaceutical solid dispersion. SOLUTION In order to solve the above-mentioned problem, a composition of the present invention comprises a low-solubility drug and at least one polymer. At least the majority of the drug in the dispersion is It is amorphous. The polymer has a glass transition temperature of at least 100 ° C. measured at 50% relative humidity. Another aspect of the invention has the same composition, except that the dispersion has a glass transition temperature of at least 50 ° C. at 50% relative humidity. In another aspect of the invention, the composition comprises a low solubility pharmaceutical and a stabilizing polymer. At least the majority of the medicament in the dispersion is amorphous. The composition also includes a concentration-enhancing polymer that increases the concentration of the drug in the environment of use. The stabilized polymer has a higher glass transition temperature than the glass transition temperature of the concentration-enhancing polymer at 50% relative humidity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011152297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9074020-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022000464-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7013454-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008524291-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7277534-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961251-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010505901-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009539804-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010529964-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004534811-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828259-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017523206-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011057958-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019534886-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005523895-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013227324-A |
| priorityDate |
1999-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |