| abstract |
(57) [Summary] [Constitution] General formula [1] [Wherein A is (Here, R 2 is a lower alkyl group substituted with a halogen atom, R 3 is a halogen atom or a lower alkyl group, R 4 is a lower alkyl group, and R 5 is a lower alkyl group.) And R 1 is a hydrogen atom, a lower alkyl group, an aryl group, a cycloalkyl group or an aralkyl group. Or a pharmaceutically acceptable salt thereof. The antidiabetic agent of the present invention has an excellent hypoglycemic effect in a hyperglycemic state, and has no effect on blood glucose in a normal or hypoglycemic state. Does not cause serious side effects such as It is useful as a therapeutic agent for diabetes and also as a preventive agent for chronic complications of diabetes. |