http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000178296-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_097405822d505467fd50f7100022cd56 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 |
| filingDate | 1998-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba3c9236e290c75f7ce3a478cdfdf538 |
| publicationDate | 2000-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2000178296-A |
| titleOfInvention | Method for synthesizing peptide-nucleotide complex |
| abstract | PROBLEM TO BE SOLVED: To provide a peptide-nucleotide complex with high purity and yield by easily and under moderate conditions by selecting an appropriate protecting group. A possible synthesis method is provided. A phosphoramidite of a peptide or amino acid having a C-terminal protected by an allyl group and an N-terminal protected by an allyloxycarbonyl group, a phosphoramidite having a phosphate moiety protected by an aryl group and a nucleic acid base moiety having an allyloxy group By reacting the phosphoramidite form with the terminal hydroxyl group of the polynucleotide by reacting with the polynucleotide protected by the carbonyl group, a complex bound via a phosphodiester bond is formed, and then the complex is removed. Synthetic method to protect. Deprotection can be performed under neutral conditions in the presence of a palladium catalyst. |
| priorityDate | 1998-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.