| abstract |
PROBLEM TO BE SOLVED: To provide a small molecule useful for treating or preventing various bone diseases or neurological diseases by specifically enhancing the action of a cell differentiation inducing factor present in a living body. Compounds are provided. [Solving Means] [In the formula, R 1 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, R 2 represents an alkyl group having 1 to 5 carbon atoms or a hydroxyl group, and R 3 represents a cyano group or CONR 4 R 5 (wherein, R 4 and R 5 are a hydrogen atom, a carbon atom number 1 to 5 represents an alkyl group and the like. ) Represents a group represented by Ar is an unsubstituted or substituted, (Wherein XYZ is NCS, NCN, NCO, CSC, COC, CNC, CNS, NNO, The element sequence of NNS, NON, NSN or NNN is shown. ) Represents an aromatic 5-membered ring, wherein n is 0 A thiophenecarboxamide compound or a salt thereof. |