http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000166542-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1010e3862914acdd087e73d76911ec6d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
filingDate | 1998-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3a1d4dfa2592093129717552ba7419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_670e363646a70629a7fa605910476cad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0526b496557f9c646bbedaf3c3244f25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfec6e5c96eda56bdc5f06f73d8e2431 |
publicationDate | 2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2000166542-A |
titleOfInvention | F-box protein of ubiquitin ligase SCF complex that promotes ubiquitination of IκB or β-catenin |
abstract | PROBLEM TO BE SOLVED: To clarify the molecular mechanism of ubiquitination of IκB and β-catenin, which are important molecules for the physiological functions of higher organisms including humans, and to carry out the ubiquitin ligase SCF complex which specifically regulates the ubiquitination. It provides the body, especially its F-box protein. SOLUTION: Skp1 protein, Cul1 protein, And an F-box protein complex comprising an F-box motif and a WD40 repeat motif (SCF complex), which promotes ubiquitination of IκB or β-catenin. A box motif protein having the amino acid sequence represented by SEQ ID NO: 1; an F-box protein of the ubiquitin ligase SCF complex, A protein having the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 3; and an F-box motif protein or a gene encoding the F-box protein. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008537115-A |
priorityDate | 1998-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.