abstract |
PROBLEM TO BE SOLVED: To provide a composition which can be formulated with a high or very high content of a water-soluble and / or water-miscible substance without deteriorating the pharmaceutical quality or other properties of the composition. To do. SOLUTION: (a) The content of water and optionally water-soluble substances totaling at least 80% by weight, based on the total weight of the formulation, and the lipids, emulsifiers and lipophilic components totaling at most 20% by weight. (B) containing at least one surfactant selected from the group of alkyl methicone copolyols and / or alkyl dimethicone copolyols, and (c) one or more containing a lipid phase of the emulsion. Water-in-oil containing more lipid components, (d) a weight ratio of (b) to (c) selected from the range of 0.10 to 0.25, and (e) also containing at least one cationic polymer emulsion. |