| abstract |
[PROBLEMS] To provide 2-alkylpyrrolidines in the treatment of diabetes and to provide pharmaceutical compositions containing these compounds. A compound represented by the following formula (I). Wherein R 1 is hydrogen, acyl, alkene, cycloalkyl, or optionally one or more hydroxy, alkoxy, amino, N-alkylamino, N, N-dialkylamino, R 2 is hydrogen or alkyl; R 3 and R 4 may be the same or different and independently of one another, hydrogen, cycloalkyl, alkyl optionally substituted with phenyl, or alkoxycarbonyl; R 5 is hydroxy, halogen, amino, N-alkylamino, N, N, halogen, hydroxy, mercapto, or amino optionally substituted with alkyl or aralkyl. -Alkyl substituted with dialkylamino or mercapto. ] |