Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef1d544029236a6dde90b902bd75f8ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate |
1998-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59f00dcd5380b7b41f6b59ab75fba154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1bda164b86ce4807ed8e794dd21c950 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_274fa5d260d1f3c5beef3134d5c63ad7 |
publicationDate |
2000-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2000093043-A |
titleOfInvention |
LIG-1 gene deficient animal |
abstract |
(57) [Problem] To provide a non-human animal lacking the function of LIG-1 gene. Also, skin diseases (such as psoriasis) The present invention provides a pathological model animal, and further provides a means for screening or identifying a therapeutic or prophylactic agent for a skin disease (such as psoriasis). A non-human animal deficient in the function of the LIG-1 gene and progeny thereof. In addition, a manufacturing method thereof. A method for screening or identifying a therapeutic or preventive agent for a skin disease, which comprises administering a test substance to the animal and detecting the drug as having an effect of improving skin lesions. A drug screened or identified by the method. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5054519-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007007787-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8309792-B2 |
priorityDate |
1998-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |