| abstract |
(57) [Problem] To provide a method for improving sustainability and workability of sustained-release microspheres using an oil-based matrix. SOLUTION: Hardened fat, long chain fatty alcohol, H A mixture of components selected from higher fatty acid polyhydric alcohol partial esters having an LB of 11 or less is melted and liquefied, the drug is dispersed therein, and microspheres are produced by centrifugal spraying. |