| abstract |
PROBLEM TO BE SOLVED: To elucidate factors that can be used to screen a compound for antibiotic activity and can also be used to determine its role in the pathogenesis of infection, dysfunction and disease. Is desired. The present invention provides an isolated polynucleotide comprising a polynucleotide having at least 70% identity to a polynucleotide encoding a polypeptide consisting of the amino acid sequence of SEQ ID NO: 2 or 4; Polynucleotides encoding polypeptides and gidA2 polypeptides and methods for their production by recombinant techniques. Further, there is provided a method of utilizing a gidA2 polypeptide to screen for antimicrobial compounds. |