http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000072759-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14b02369b953bf4ebd31190c8cb63473 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-538 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 1998-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8b3ded3f0d6d524429b19dbda498039 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a5577429ea1f5ce180847511207bebe |
publicationDate | 2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2000072759-A |
titleOfInvention | 8-position substituted benzo [1,4] oxazine derivative |
abstract | (57) [Problem] To provide a novel 8-substituted benzo [1,4] oxazine derivative or a pharmacologically acceptable salt. Kind Code: A1 Abstract: Formula (I) (Wherein, R 1 represents a lower alkyl group, and R 2 and R 3 represents the same or different and represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom or a lower alkoxy group. Or a pharmacologically acceptable salt thereof. [Effect] The above compound exhibits an excellent Na + / H + exchange mechanism inhibitory action. Therefore, a medicament containing the compound as an active ingredient, a disorder induced by acidosis during myocardial ischemia, For example, it is useful as an agent for preventing and treating cardiac dysfunction, myocardial necrosis and arrhythmia, which are seen in ischemic heart diseases such as myocardial infarction and angina. |
priorityDate | 1998-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.