abstract |
PROBLEM TO BE SOLVED: To provide a drug having a strong action on a group 2 metabotropic glutamate receptor having a therapeutic effect and a preventive effect on a psychiatric disorder or a neurological disease. SOLUTION: The formula: Or Wherein Y 1 and Y 2 are the same or different and each have 1 carbon atom. Or shows a -10 lower alkylthio group, or shows a -S (CH 2) n S- group (where n is 2 or 3.) Is both. R 1 and R 2 are the same or different and each represent a hydrogen atom, Or a lower alkyl group having 1 to 10 carbon atoms. 4-substituted-2-aminobicyclo [3.1.0] hexane-2,6-dicarboxylic acid derivative or a pharmaceutically acceptable salt thereof. |