Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ef01e33058cf740cf2197991be97af1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-02 |
filingDate |
1998-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da8a2c32e9bb8129eed7a6aed3634855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f95594f5b990158f0786365917151e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb138b064aabf14080eeadef80b7816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad1148e0ceb150b60a30c3756804e317 |
publicationDate |
2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2000072728-A |
titleOfInvention |
Method for producing optically active α-substituted-β-aminoketone derivative |
abstract |
(57) [Summary] [Problem] An optically active aluminum which is a multifunctional composite metal complex in the presence of a Lewis acid without synthesizing a racemic compound and then removing unnecessary optical isomers by optical resolution in the presence of a Lewis acid. Provided is a method for directly producing an optically active α-substituted-β-aminoketone derivative from an optically inactive starting material by an asymmetric Mannich reaction using an α-aminoether using an alkali metal-binaphthol complex as a catalyst. I do. SOLUTION: (General formula 1): A process for producing an optically active α-substituted-β-aminoketone derivative by carrying out an asymmetric Mannich reaction using an optically active aluminum-alkali metal-binaphthol complex, a Lewis acid and an α-aminoether derivative as shown in (1). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011111426-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009023989-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1623971-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1623971-A1 |
priorityDate |
1998-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |