http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000026470-A

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filingDate 1998-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17a11bc5a3f7cd693ed6806f52409a72
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publicationDate 2000-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2000026470-A
titleOfInvention Method for producing 3-cephem compound
abstract PROBLEM TO BE SOLVED: To provide a method for obtaining a cephem compound of the general formula (3) stably and in high yield without isolating an unstable compound generated by a conventional method. . SOLUTION: After reacting a β-lactam compound represented by the general formula (1) with a phosphorus halide compound in the presence of an organic base, an imino-β-lactam compound represented by the general formula (2) is obtained. Phenols are added to the same reaction system to carry out alcoholysis, and at the same time, deprotection of a carboxylic acid ester to obtain a 3-cephem compound represented by the general formula (3) or a salt thereof. A method for producing a cephem compound. Wherein R 1 is an arylmethyl group or the like, R 2 is a hydrogen atom, R 3 such as a halogen atom, such as a benzyl group which may have an electron donating group on the phenyl ring, and X represents a halogen atom.]
priorityDate 1998-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 24.